[Trucker12]

Any idea why my truck would shake when I pick up speed. It usually does not start to shake until I hit about 60 on the highway. You can feel it on the floor and the steering wheel?

[Rockett]

Start looking at your suspension, axle, drivetrain, anything of that nature. You didn't say what kind of truck you drive, so it's a little hard to tell.
But this is defintely something you don't want to ignore.

[cruisin]

I would probably start by looking at the tires. Be sure there is proper air in them and that they are not worn uneven. If this isn't it, then you can look at the struts and other things.

[Ottoman]

I would check the tires; rotation, condition, etc. Then I would check the alignment. Take it in to a service center and have a diagnostic done.